Best Grey's Anatomy Patients of All Time, Ranked

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Grey's Anatomy on ABC

We obviously love the doctors, but sometimes we forget about the awesome patients of Grey's Anatomy. The patients are one of the hardest parts about watching Grey's because we never really know how long we'll have with them. From the moment we meet them, we know there is a 50% chance they will die. Shonda Rhimes has already decided from the beginning whether they will live or die, so there's really no point in having any sort of hope.

Over the years, we've learned to make the most of the time we have with the Grey's patients. Sometimes they even teach everyone in the hospital a much-needed lesson. There is much to be learned and appreciated about the amazing Grey's Anatomy patients, and we never know what we're going to get!

One thing is for sure, we're definitely picking favorites when it comes to patients. Some of them just seem like a total pain to have in the hospital, and others we hate to see leave.

Check out our ranking of the best Grey's Anatomy patients of all time, you'll probably agree! So, don't forget to vote for your favorite (and least favorite) patients!

Did we miss your favorite patient? Let us know!

  • Denny Duquette

    Community Score: 10
    Grey's Anatomy via ABC

    Denny Duquette (Jeffrey Dean Morgan) seemed to be a favorite patient on Grey's Anatomy. All of the doctors loved having him around, especially Izzie Stevens (Katherine Heigl) who literally fell in love with him. Denny was one of the hardest patients for us to let go of too!

  • Henry Burton

    Community Score: 8
    Grey's Anatomy on ABC

    We will never forgive Shonda Rhimes for killing this one off. Henry Burton (Scott Foley) was the husband of Teddy Altman (Kim Raver) who brought nothing but joy to the hospital. Not to mention, he was a total delight to look at. We miss you, Henry.

  • Harold O'Malley

    Community Score: 7
    Grey's Anatomy on ABC

    George O'Malley's (T.R. Knight) father, Harold O'Malley (George Dzundza) was one of our favorites. He was a great father to his three sons, and a pleasure to have at the hospital. We totally didn't expect for his health to deteriorate so quickly, cutting our time with him short.

  • Jessica Smithson

    Community Score: 5
    Grey's Anatomy on ABC

    Jessica Smithson (Mary-Charles Jones), the little angel that was diagnosed with Tay-Sachs should have never died. She was so young and precious, even Miranda Bailey (Chandra Wilson) had a soft spot for her. It was hard enough watching her be taken from us, but seeing her father breakdown was a whole different story!

  • Ryan

    Community Score: 4
    Grey's Anatomy on ABC

    On Halloween, Ryan (Dylan Minnette) showed up to the hospital to ask Mark Sloan (Eric Dane) to build him ears. Ryan was born with the internal structure to hear, but no external ears. He was completely adorable and Mark was glad to do the surgery for free. We haven't seen Ryan since he left the hospital with his new ears, but we would love to see him come back one day!

  • Beth Monroe

    Community Score: 4
    Grey's Anatomy on ABC

    Beth Monroe's (Jurnee Smollett-Bell) survival story marked a turning point in Derek Shepherd (Patrick Dempsey) and Meredith Grey's (Ellen Pompeo) clinical trial. She was actually the first person to survive the trial, which is what made her so memorable. Unfortunately for Beth, her boyfriend did not survive the trial.

  • Gladys Pulcher

    Community Score: 4
    Grey's Anatomy on ABC

    Gladys Pulcher (Doris Roberts) was a bit of a difficult patient of Alex's on Grey's Anatomy. She suffered from lung cancer and later died in the hospital after failing to properly recover from a surgery. After she died, it's revealed that she donated $200,000 to Alex's African orphan project. It turns out she wasn't so bad after all.

  • Camille Travis

    Community Score: 3
    Grey's Anatomy on ABC

    Richard Webber's (James Pickens Jr.) niece, Camille Travis (Tessa Thompson) was admitted to the hospital on her prom night after losing consciousness during sex. It turned out Camille had a history of ovarian cancer. Webber decided to move her prom to the hospital, making attendance mandatory for all of the doctors. It was heartwarming to see that her prom night wasn't totally ruined.

  • Alison Clark

    Community Score: 2
    Grey's Anatomy on ABC

    We really enjoyed the short time we had on Grey's with Alison Clark (Liza Weil). She was a cancer patient who befriended Izzie when the two had to go for chemotherapy treatments. Alison was a total sweetheart, and it was devastating to see her die so young.

  • Beatrice Carver

    Community Score: 0
    Grey's Anatomy on ABC

    Beatrice Carver (Laurie Metcalf) was a total sweetheart. Unfortunately, her cancer was deemed terminal and Alex had to help her understand she could die at any moment. Beatrice did everything she could to hide her illness from her daughter, but she finally gave in at the end. It was difficult on everyone (especially us!) when she finally ended up dying.

  • Charlie Lowell

    Community Score: -1
    Grey's Anatomy via ABC

    His dedication to serving his country is what really made us admire Charlie Lowell (Zach Gilford). He came to the hospital begging Callie Torres (Sara Ramirez) to amputate his leg even though she found nothing wrong with it. He complained of severe pain and believed he would not be able to return to the Army without the procedure. Callie went ahead and removed the leg at his request.

  • Jimmy Evans

    Community Score: -2
    Grey's Anatomy on ABC

    Jimmy Evans (James Remar) was better known as Alex Karev's (Justin Chambers) father. He abandoned his family, causing Alex to miss out on ever having a relationship with his father. Unfortunately, Jimmy died at the hospital and we never got to see what could have been. Jimmy might've not had the brightest past, but we wanted to see Alex happy.