Side-By-Side Pics Of Kelly Osbourne That Have Fueled 'Ozempic Hands' Accusations
To say Kelly Osbourne's appearance has changed drastically would be an understatement. While the star's weight struggles have been publicly documented since her time on her family's TV show, "The Osbournes", her noticeable weight loss has become difficult to ignore. In post shared to Instagram in February 2026, Osbourne can be seen pictured wearing a skin-tight, long-sleeved turtleneck dress, with her hair put up in a messy bun. However, some fans weren't as drawn to her polished look as they were to her appearance , which served to inflame accusations of 'Ozempic hands'.
"What the hell is going on with her hands?" one Instagram user commented. Another user noted, "Omg she looks so skinny that her hands look bigger than her waist." According to Bolt Pharmacy, Ozempic hands is not a medically recognized term, and instead refers to an unusual side effect from GLP-1 use. As such, it's understandable why fans are taking note of this on Osbourne, as side-by-side photos of the star from 2012 and 2026 indicate a clear difference in her hands. In the more recent image on the right, her hands nearly encircle her waist, with her knuckles appearing more prominent. The post was made only a day after the reality star attended the 2026 Grammys, and Osbourne's appearance didn't help the rumors buzzing of a plastic surgery and Ozempic takeover.
Despite these rumors, Osbourne has denied taking Ozempic or any other GLP-1 variants, instead stating that her sudden change in appearance was a physical byproduct of processing the grief of losing her father, Ozzy Osbourne, on July 2025. "To be honest with you, I won't lie. ... I'm not doing so great," Kelly shared on the Grammys red carpet, after being asked how she was coping with Ozzy's passing (via OK). Still, this doesn't mean Osbourne hasn't ever turned to medical intervention to assist with weight management.
Kelly Osbourne has had a dramatic weight loss journey
While it's undeniable that Kelly Osbourne has totally transformed over the years, the former "Fashion Police" co-host has been quite open about what she's done to achieve it. Back in 2020, she shared with "The Hollywood Raw" podcast that she had gastric sleeve surgery in 2018 and, alongside a combination of healthy eating and exercise, lost 85 pounds. However, she later gained 100 pounds during her pregnancy with son, Sidney (born in 2022). When later discussing how she lost the baby weight, Osbourne credited a strict diet of "no sugar, no carbohydrates" (via People) and body sculpting treatments, such as EMFACE and EMSCULPT, to tighten her face and figure. "I had the baby and my stomach got so many stretch marks, and the skin, it looks like it lost its elasticity," she told Extra.
But what could explain the further change in her appearance? Aside from allegations of Ozempic use, the star has been lobbed with accusations of plastic surgery as well. While Kelly Osbourne has made her opinions on plastic surgery known to the public, she has also denied having gone under the knife. The TV personality set the record straight in an Instagram clip she posted in May 2021. "I have not had plastic surgery. I've never done anything to my face, other than a couple of injections in my lips, in my jaw, and in my forehead here."